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Three-Dimensional Heterocycles: New Uracil-Based Structures Obtained by Nucleophilic Substitution at the sp(2) Carbon of Bromoisoxazoline

The regioisomeric cycloadducts of bromonitrile oxide and N-benzoyl-2,3-oxaza-norborn-5-ene were easily prepared and elaborated into a novel class of uracil-based scaffolds. The key-synthetic step is the nucleophilic substitution at the sp(2) carbon atom of the bromoisoxazoline three-dimensional hete...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Memeo, Misal Giuseppe, Lapolla, Francesco, Bovio, Bruna, Quadrelli, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271772/
https://ncbi.nlm.nih.gov/pubmed/24962398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19068661
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