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Isolation, Structural Analyses and Biological Activity Assays against Chronic Lymphocytic Leukemia of Two Novel Cytochalasins — Sclerotionigrin A and B

Two new cytochalasins, sclerotionigrin A (1) and B (2) were isolated together with the known proxiphomin (3) from the filamentous fungus Aspergillus sclerotioniger. The structures and relative stereochemistry of 1 and 2 were determined based on comparison with 3, and from extensive 1D and 2D NMR spe...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Petersen, Lene M., Bladt, Tanja T., Dürr, Claudia, Seiffert, Martina, Frisvad, Jens C., Gotfredsen, Charlotte H., Larsen, Thomas O.
Format: Artigo
Langue:Inglês
Publié: MDPI 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271702/
https://ncbi.nlm.nih.gov/pubmed/25006786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19079786
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