Deguelin Inhibits the Migration and Invasion of U-2 OS Human Osteosarcoma Cells via the Inhibition of Matrix Metalloproteinase-2/-9 in Vitro

Osteosarcoma is the most common malignant primary bone tumor in children and young adults and lung metastasis is the main cause of death in those patients. Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to exhibit cytotoxic effects, including antiproliferative and anti...

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Publicado no:Molecules
Main Authors: Shang, Hung-Sheng, Chang, Jin-Biou, Lin, Ju-Hwa, Lin, Jing-Pin, Hsu, Shu-Chun, Liu, Chi-Ming, Liu, Jia-You, Wu, Ping-Ping, Lu, Hsu-Feng, Au, Man-Kuan, Chung, Jing-Gung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271177/
https://ncbi.nlm.nih.gov/pubmed/25322282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191016588
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