GSK3β Regulates Milk Synthesis in and Proliferation of Dairy Cow Mammary Epithelial Cells via the mTOR/S6K1 Signaling Pathway

Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase, whose activity is inhibited by AKT phosphorylation. This inhibitory phosphorylation of GSK3β can in turn play a regulatory role through phosphorylation of several proteins (such as mTOR, elF2B) to promote protein synthesis. mTOR is a ke...

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Vydáno v:Molecules
Hlavní autoři: Zhang, Xia, Zhao, Feng, Si, Yu, Huang, Yuling, Yu, Cuiping, Luo, Chaochao, Zhang, Na, Li, Qingzhang, Gao, Xuejun
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271057/
https://ncbi.nlm.nih.gov/pubmed/24995926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19079435
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