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Starvation in the Midst of Plenty: Reflections on the History and Biology of Insulin and Leptin

Insulin and leptin are critical metabolic hormones that play essential but distinct roles in regulating the physiologic switch between the fed and starved states. The discoveries of insulin and leptin, in 1922 and 1994, respectively, arose out of radically different scientific environments. Despite...

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Detalhes bibliográficos
Publicado no:Endocr Rev
Autor principal: Flier, Jeffrey S
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270967/
https://ncbi.nlm.nih.gov/pubmed/30357355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2018-00179
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