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Penostatin Derivatives, a Novel Kind of Protein Phosphatase 1B Inhibitors Isolated from Solid Cultures of the Entomogenous Fungus Isaria tenuipes

Protein tyrosine phosphatase 1B (PTP1B) is implicated as a negative regulator of insulin receptor (IR) signaling and a potential drug target for the treatment of type II diabetes and other associated metabolic syndromes. Therefore, small molecular inhibitors of PTP1B can be considered as an attracti...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chen, Yu-Peng, Yang, Chun-Gui, Wei, Pei-Yao, Li, Lin, Luo, Du-Qiang, Zheng, Zhi-Hui, Lu, Xin-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270892/
https://ncbi.nlm.nih.gov/pubmed/24481115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19021663
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