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Reduction of the Nitro Group to Amine by Hydroiodic Acid to Synthesize o-Aminophenol Derivatives as Putative Degradative Markers of Neuromelanin

Neuromelanin (NM) is produced in dopaminergic neurons of the substantia nigra (SN) and in noradrenergic neurons of the locus coeruleus (LC). The synthesis of NM in those neurons is a component of brain aging and there is the evidence that this pigment can be involved in the pathogenesis of neurodege...

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Vydáno v:Molecules
Hlavní autoři: Wakamatsu, Kazumasa, Tanaka, Hitomi, Tabuchi, Keisuke, Ojika, Makoto, Zucca, Fabio A., Zecca, Luigi, Ito, Shosuke
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270749/
https://ncbi.nlm.nih.gov/pubmed/24936706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19068039
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