Bioactive Secondary Metabolites of a Marine Bacillus sp. Inhibit Superoxide Generation and Elastase Release in Human Neutrophils by Blocking Formyl Peptide Receptor 1

It is well known that overwhelming neutrophil activation is closely related to acute and chronic inflammatory injuries. Formyl peptide receptor 1 (FPR1) plays an important role in activation of neutrophils and may represent a potent therapeutic target in inflammatory diseases. In the present study,...

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Bibliographic Details
Published in:Molecules
Main Authors: Yang, Shun-Chin, Lin, Chwan-Fwu, Chang, Wen-Yi, Kuo, Jimmy, Huang, Yin-Ting, Chung, Pei-Jen, Hwang, Tsong-Long
Format: Artigo
Language:Inglês
Published: MDPI 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270428/
https://ncbi.nlm.nih.gov/pubmed/23736784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18066455
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