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Determining Chemical Reactivity Driving Biological Activity from SMILES Transformations: The Bonding Mechanism of Anti-HIV Pyrimidines

Assessing the molecular mechanism of a chemical-biological interaction and bonding stands as the ultimate goal of any modern quantitative structure-activity relationship (QSAR) study. To this end the present work employs the main chemical reactivity structural descriptors (electronegativity, chemica...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Putz, Mihai V., Dudaş, Nicoleta A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270382/
https://ncbi.nlm.nih.gov/pubmed/23903183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18089061
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