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Sodium Valproate Induces Cell Senescence in Human Hepatocarcinoma Cells

Hepatocarcinogenesis is associated with epigenetic changes, including histone deacetylases (HDACs). Epigenetic modulation by HDAC inhibition is a potentially valuable approach for hepatocellular carcinoma treatment. In present study, we evaluated the anticancer effects of sodium valproate (SVP), a k...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: An, Hong-Mei, Xue, Yong-Fei, Shen, Yan-Li, Du, Qin, Hu, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270308/
https://ncbi.nlm.nih.gov/pubmed/24304587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181214935
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