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Anti-Inflammatory Effect of Neoechinulin A from the Marine Fungus Eurotium sp. SF-5989 through the Suppression of NF-кB and p38 MAPK Pathways in Lipopolysaccharide-Stimulated RAW264.7 Macrophages

In the course of a bioassay-guided study of metabolites from the marine fungus Eurotium sp. SF-5989, two diketopiperazine type indole alkaloids, neoechinulins A and B, were isolated. In this study, we investigated the anti-inflammatory effects of neoechinulins A (1) and B (2) on lipopolysaccharide (...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: Kim, Kyoung-Su, Cui, Xiang, Lee, Dong-Sung, Sohn, Jae Hak, Yim, Joung Han, Kim, Youn-Chul, Oh, Hyuncheol
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270177/
https://ncbi.nlm.nih.gov/pubmed/24165583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181113245
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