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In Vitro and in Vivo Anticancer Activity of Aconitine on Melanoma Cell Line B16

The anti-tumor effect of aconitine in melanoma cell line B16 has been studied in this paper. We found that B16 cells showed significantly reduced growth rates and increased apoptotic effects in the presence of aconitine. Furthermore, aconitine inhibited the PI3K/AKT and MAPK/ERK1/2 signaling pathway...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Du, Juan, Lu, Xiaonian, Long, Ziwen, Zhang, Zhen, Zhu, Xiaohua, Yang, Yongsheng, Xu, Jinhua
Format: Artigo
Langue:Inglês
Publié: MDPI 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270132/
https://ncbi.nlm.nih.gov/pubmed/23299553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18010757
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