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Highly Enantioselective Addition of Phenylethynylzinc to Aldehydes Catalyzed by Chiral Cyclopropane-Based Amino Alcohols

The enantioselective addition of phenylethynylzinc to aldehydes catalyzed by a series of cyclopropane-based amino alcohol ligands 7 was investigated. The reactions afforded chiral propargylic alcohols in high yields (up to 96%) and with excellent enantioselectivities (up to 98% ee) under mild condit...

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Vydáno v:Molecules
Hlavní autoři: Zheng, Bing, Li, Zhiyuan, Liu, Feipeng, Wu, Yanhua, Shen, Junjian, Bian, Qinghua, Hou, Shicong, Wang, Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270052/
https://ncbi.nlm.nih.gov/pubmed/24335619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181215422
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