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Conformational Analysis of Geometric Isomers of Pitavastatin Together with Their Lactonized Analogues

Super-statins are synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, which is the rate-limiting enzyme responsible for the biosynthesis of cholesterol. All of the super-statins with a C=C double bond spacer between the heterocyclic and the dihydroxycarboxylic moiety that are cu...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Makuc, Damjan, Fabris, Jan, Časar, Zdenko, Plavec, Janez
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270003/
https://ncbi.nlm.nih.gov/pubmed/24169468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181113283
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