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Induction of Apoptosis by Costunolide in Bladder Cancer Cells is Mediated through ROS Generation and Mitochondrial Dysfunction

Despite the availability of several therapeutic options, a safer and more effective modality is urgently needed for treatment of bladder cancer. Costunolide, a member of sesquiterpene lactone family, possesses potent anticancer properties. In this study, for the first time we investigated the effect...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Molecules
Main Authors: Rasul, Azhar, Bao, Rui, Malhi, Mahadev, Zhao, Bing, Tsuji, Ichiro, Li, Jiang, Li, Xiaomeng
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269911/
https://ncbi.nlm.nih.gov/pubmed/23348995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18021418
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