Synthesis, Antifungal and Antitumor Activity of Novel (Z)-5-Hetarylmethylidene-1,3-thiazol-4-ones and (Z)-5-Ethylidene-1,3-thiazol-4-ones

New hetaryl- and alkylidenerhodanine derivatives 3a–d, 3e, and 4a–d were prepared from heterocyclic aldehydes 1a–d or acetaldehyde 1e. The treatment of several rhodanine derivatives 3a–d and 3e with piperidine or morpholine in THF under reflux, afforded (Z)-5-(hetarylmethylidene)-2-(piperidin-1-yl)t...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Insuasty, Alberto, Ramírez, Juan, Raimondi, Marcela, Echeverry, Carlos, Quiroga, Jairo, Abonia, Rodrigo, Nogueras, Manuel, Cobo, Justo, Rodríguez, María Victoria, Zacchino, Susana A., Insuasty, Braulio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269731/
https://ncbi.nlm.nih.gov/pubmed/23669632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18055482
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