Preparation and Optimization of Triptolide-Loaded Solid Lipid Nanoparticles for Oral Delivery with Reduced Gastric Irritation

Triptolide (TP) often causes adverse reactions in the gastrointestinal tract when it is administered orally. This study aimed to prepare and optimize triptolide-loaded solid lipid nanoparticles (TP-SLN) with reduced gastric irritation. The microemulsion technique was used to formulate TP-SLN employi...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhang, Cong, Gu, Conghui, Peng, Fan, Liu, Wei, Wan, Jiangling, Xu, Huibi, Lam, Christopher Waikei, Yang, Xiangliang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269717/
https://ncbi.nlm.nih.gov/pubmed/24172242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181113340
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