Preparation and Optimization of Triptolide-Loaded Solid Lipid Nanoparticles for Oral Delivery with Reduced Gastric Irritation

Triptolide (TP) often causes adverse reactions in the gastrointestinal tract when it is administered orally. This study aimed to prepare and optimize triptolide-loaded solid lipid nanoparticles (TP-SLN) with reduced gastric irritation. The microemulsion technique was used to formulate TP-SLN employi...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Zhang, Cong, Gu, Conghui, Peng, Fan, Liu, Wei, Wan, Jiangling, Xu, Huibi, Lam, Christopher Waikei, Yang, Xiangliang
Format: Artigo
Langue:Inglês
Publié: MDPI 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269717/
https://ncbi.nlm.nih.gov/pubmed/24172242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181113340
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