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Synthesis and SAR Studies of Praziquantel Derivatives with Activity against Schistosoma japonicum

The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described. Several of them showed better worm killing activity than praziquantel and could serve as leads for further optimization.

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Podrobná bibliografie
Vydáno v:Molecules
Hlavní autoři: Wang, Wen-Long, Song, Li-Jun, Chen, Xia, Yin, Xu-Ren, Fan, Wen-Hua, Wang, Gu-Ping, Yu, Chuan-Xin, Feng, Bainian
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269691/
https://ncbi.nlm.nih.gov/pubmed/23912271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18089163
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