The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes

Sickle cell trait, a common hereditary blood disorder, protects carriers from severe disease in infections with the human malaria parasite Plasmodium falciparum. Protection is associated with a reduced capacity of parasitized erythrocytes to cytoadhere to the microvascular endothelium and cause vaso...

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Publicat a:Commun Biol
Autors principals: Lansche, Christine, Dasanna, Anil K., Quadt, Katharina, Fröhlich, Benjamin, Missirlis, Dimitris, Tétard, Marilou, Gamain, Benoit, Buchholz, Bernd, Sanchez, Cecilia P., Tanaka, Motomu, Schwarz, Ulrich S., Lanzer, Michael
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269544/
https://ncbi.nlm.nih.gov/pubmed/30534603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0223-3
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