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Administration of antibiotics contributes to cholestasis in pediatric patients with intestinal failure via the alteration of FXR signaling

The link between antibiotic treatment and IF-associated liver disease (IFALD) is unclear. Here, we study the effect of antibiotic treatment on bile acid (BA) metabolism and investigate the involved mechanisms. The results showed that pediatric IF patients with cholestasis had a significantly lower a...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Xiao, Yongtao, Zhou, Kejun, Lu, Ying, Yan, Weihui, Cai, Wei, Wang, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269533/
https://ncbi.nlm.nih.gov/pubmed/30504803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0181-3
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