Cargando...

Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives

Several acridine derivatives were synthesized and their anti-proliferative activity was determined. The most active molecules were derivatives of 5-methylacridine-4-carboxylic acid. The DNA binding properties of the synthesized acridines were analyzed by competitive dialysis and compared with the an...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Ferreira, Rubén, Aviñó, Anna, Mazzini, Stefania, Eritja, Ramon
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269017/
https://ncbi.nlm.nih.gov/pubmed/22683895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17067067
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!