Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones

Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with carbohydrate. Most of the title compounds exhi...

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Publicado no:Molecules
Main Authors: Lou, Qinghua, Meng, Xiangbao, Lao, Zhiqi, Xuan, Lingling, Bai, Jinye, Hou, Qi, Hu, Gaoyun, Luo, Renna, Tao, Lijian, Li, Zhongjun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269014/
https://ncbi.nlm.nih.gov/pubmed/22252504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17010884
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