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An Efficient Synthesis of Novel Dispirooxindole Derivatives via One-Pot Three-Component 1,3-Dipolar Cycloaddition Reactions

A series of novel dispirooxindoles have been synthesized through three-component 1,3-dipolar cycloaddition of azomethine ylides generated in situ by the decarboxylative condensation of isatin and an α-amino acid with the dipolarophile 5-benzylidene-1,3-dimethylpyrimidine-2,4,6-trione. This method ha...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Huang, Zhibin, Zhao, Qian, Chen, Gang, Wang, Huiyuan, Lin, Wei, Xu, Lexing, Liu, Hongtao, Wang, Juxian, Shi, Daqing, Wang, Yucheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269013/
https://ncbi.nlm.nih.gov/pubmed/23103534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules171112704
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