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Computational Prediction of Blood-Brain Barrier Permeability Using Decision Tree Induction

Predicting blood-brain barrier (BBB) permeability is essential to drug development, as a molecule cannot exhibit pharmacological activity within the brain parenchyma without first transiting this barrier. Understanding the process of permeation, however, is complicated by a combination of both limit...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Suenderhauf, Claudia, Hammann, Felix, Huwyler, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269008/
https://ncbi.nlm.nih.gov/pubmed/22941223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules170910429
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