The Effect of β-Carotene Supplementation on the Pharmacokinetics of Nelfinavir and Its Active Metabolite M8 in HIV-1-infected Patients

β-Carotene supplements are often taken by individuals living with HIV-1. Contradictory results from in vitro studies suggest that β-carotene may inhibit or induce cytochrome P450 enzymes and transporters. The study objective was to investigate the effect of β-carotene on the steady-state pharmacokin...

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Publicat a:Molecules
Autors principals: Sheehan, Nancy L., van Heeswijk, Rolf P. G., Foster, Brian C., Akhtar, Humayoun, Singhal, Neera, Seguin, Isabelle, DelBalso, Lina, Bourbeau, Marc, Chauhan, Bobby M., Boulassel, Mohammed-Rachid, Burger, David M., Lalonde, Richard G., Cameron, Donald William
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268962/
https://ncbi.nlm.nih.gov/pubmed/22241465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17010688
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