Synthesis and Biological Activity of Some 3-(4-(Substituted)-piperazin-1-yl)cinnolines

A new series of 6-substituted-4-methyl-3-(4-arylpiperazin-1-yl)cinnolines 8–10 were synthesized as potential antifungal agents via intramolecular cyclization of the respective 1-(2-arylhydrazono)-1-(4-arylpiperazin-1-yl)propan-2-ones 5–7, mediated by polyphosphoric acid (PPA). The amidrazones themse...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Awad, Eman D., El-Abadelah, Mustafa M., Matar, Suzan, Zihlif, Malek A., Naffa, Randa G., Al-Momani, Ehab Q., Mubarak, Mohammad S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268863/
https://ncbi.nlm.nih.gov/pubmed/22205089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17010227
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