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Synthesis and Cytotoxic Activity of Some Novel N-Pyridinyl-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide Derivatives

A series of novel compounds bearing imidazo[2,1-b]thiazole scaffolds were designed and synthesized based on the optimization of the virtual screening hit compound N-(6-morpholinopyridin-3-yl)-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide (5a), and tested for their cytotoxicity against human cancer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Ding, Huaiwei, Chen, Zhe, Zhang, Cunlong, Xin, Tian, Wang, Yini, Song, Hongrui, Jiang, Yuyang, Chen, Yuzong, Xu, Yongnan, Tan, Chunyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268833/
https://ncbi.nlm.nih.gov/pubmed/22525437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17044703
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