Gossypol Exhibits a Strong Influence Towards UDP-Glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-Mediated Metabolism of Xenobiotics and Endogenous Substances

Gossypol, the polyphenolic constituent isolated from cottonseeds, has been used as a male antifertility drug for a long time, and has been demonstrated to exhibit excellent anti-tumor activity towards multiple cancer types. The toxic effects of gossypol limit its clinical utilization, and enzyme inh...

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Vydáno v:Molecules
Hlavní autoři: Zhang, Yong-Sheng, Yuan, Jun, Fang, Zhong-Ze, Tu, Yan-Yang, Hu, Cui-Min, Li, Gan, Wang, Liang, Deng, Jian-Ping, Yao, Jia-Jiu, Li, Hai-Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268803/
https://ncbi.nlm.nih.gov/pubmed/22543504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17054896
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