Synthesis and Cytotoxicity Evaluation of 13-n-Alkyl Berberine and Palmatine Analogues as Anticancer Agents

By introducing long carbon-chain alkyl groups at the C-13 position of berberine and palmatine, 13-n-hexyl/13-n-octyl berberine and palmatine chloride analogues 4a–d were synthesized and examined by MTT assays for cytotoxic activity in seven human cancer cell lines (7701QGY, SMMC7721, HepG2, CEM, CEM...

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Publicado en:Molecules
Autores principales: Zhang, Lei, Li, Jingjing, Ma, Fei, Yao, Shining, Li, Naisan, Wang, Jing, Wang, Yongbin, Wang, Xiuzhen, Yao, Qizheng
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268624/
https://ncbi.nlm.nih.gov/pubmed/23011273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules171011294
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