Synthesis and Preliminary Investigations of the siRNA Delivery Potential of Novel, Single-Chain Rigid Cationic Carotenoid Lipids

The success of nucleic acid delivery requires the development of safe and efficient delivery vectors that overcome cellular barriers for effective transport. Herein we describe the synthesis of a series of novel, single-chain rigid cationic carotenoid lipids and a study of their preliminary in vitro...

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Publicado no:Molecules
Main Authors: Pungente, Michael D., Jubeli, Emile, Øpstad, Christer L., Al-Kawaz, Mais, Barakat, Nour, Ibrahim, Tarek, Khalique, Nada Abdul, Raju, Liji, Jones, Rachel, Leopold, Philip L., Sliwka, Hans-Richard, Partali, Vassilia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268619/
https://ncbi.nlm.nih.gov/pubmed/22426529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17033484
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