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Synthesis and Bioactivity of Pyrazole Acyl Thiourea Derivatives
Sixteen novel pyrazole acyl thiourea derivatives 6 were synthesized from monomethylhydrazine (phenylhydrazine) and ethyl acetoacetate. The key 5-chloro-3-methyl-1-substituted-1H-pyrazole-4-carbonyl chloride intermediates 4 were first generated in four steps through cyclization, formylation, oxidatio...
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| Izdano u: | Molecules |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6268560/ https://ncbi.nlm.nih.gov/pubmed/22555301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17055139 |
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