Synthesis of Azanucleosides through Regioselective Ring-Opening of Epoxides Catalyzed by Sulphated Zirconia under Microwave and Solvent-Free Conditions

New azanucleosides were obtained using sulphated zirconia (ZS) as catalyst in the nucleophilic oxirane ring opening reaction of 1-allyl-3-(oxiran-2-ylmethyl)pyrimidine-2,4(1H,3H)-dione and 1-allyl-5-methyl-3-(oxiran-2-ylmethyl)-pyrimidine-2,4(1H,3H)-dione, with (S)-prolinol. The new templates were o...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Hernández-Reyes, Celia Xochitl, Angeles-Beltrán, Deyanira, Lomas-Romero, Leticia, González-Zamora, Eduardo, Gaviño, Rubén, Cárdenas, Jorge, Morales-Serna, José Antonio, Negrón-Silva, Guillermo E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268552/
https://ncbi.nlm.nih.gov/pubmed/22421790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17033359
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