Effect of Efavirenz on UDP-Glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 Activities in Human Liver Microsomes

Efavirenz is a non-nucleoside reverse transcriptase inhibitor used for the treatment of human immunodeficiency virus type 1 infections. Drug interactions of efavirenz have been reported due to in vitro inhibition of CYP2C9, CYP2C19, CYP3A4, and UDP-glucuronosyltransferase 2B7 (UGT2B7) and in vivo CY...

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Vydáno v:Molecules
Hlavní autoři: Ji, Hye Young, Lee, Hyeri, Lim, Sae Rom, Kim, Jeong Han, Lee, Hye Suk
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268312/
https://ncbi.nlm.nih.gov/pubmed/22252501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17010851
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