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Convergent Synthesis of the Potent P2Y Receptor Antagonist MG 50-3-1 Based on a Regioselective Ullmann Coupling Reaction
MG 50-3-1 (3, trisodium 1-amino-4-{4-[4-chloro-6-(2-sulfophenylamino)-1,3,5-triazin-2-ylamino]-2-sulfophenylamino}-9,10-dioxo-9,10-dihydroanthracene 2-sulfonate) is the most potent and selective antagonist (IC(50) 4.6 nM) for “P2Y(1)-like” nucleotide-activated membrane receptors in guinea-pig taenia...
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| Gepubliceerd in: | Molecules |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6268193/ https://ncbi.nlm.nih.gov/pubmed/22391596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17032599 |
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