IL-17A contributes to perioperative neurocognitive disorders through blood-brain barrier disruption in aged mice

BACKGROUND: Perioperative neurocognitive disorders (PND) occur frequently after surgery, especially in aged patients. Surgery-induced neuroinflammation and blood-brain barrier (BBB) dysfunction play a crucial role in the pathogenesis of PND. Interleukin-17A (IL-17A) increases after surgical stress a...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Ni, Pengfei, Dong, Hongquan, Wang, Yiwei, Zhou, Qin, Xu, Mengmeng, Qian, Yanning, Sun, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267879/
https://ncbi.nlm.nih.gov/pubmed/30501622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1374-3
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