Let-7a inhibits osteosarcoma cell growth and lung metastasis by targeting Aurora-B

PURPOSE: Accumulating studies showed that the expression of microRNAs (miRNAs) was dysregulated in osteosarcoma (OS). In this study, we sought to investigate the effect of let-7a on OS progression and its potential molecular mechanism. PATIENTS AND METHODS: Quantitative real-time PCR (qRT-PCR) was p...

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Vydáno v:Cancer Manag Res
Hlavní autoři: Yu, Jing-Jing, Pi, Wen-Sen, Cao, Yuan, Peng, Ai-Fen, Cao, Zhi-Yuan, Liu, Jia-Ming, Huang, Shan-Hu, Liu, Zhi-Li, Zhang, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267740/
https://ncbi.nlm.nih.gov/pubmed/30568492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S185090
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