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Foxp2 loss of function increases striatal direct pathway inhibition via increased GABA release
Heterozygous mutations of the Forkhead-box protein 2 (FOXP2) gene in humans cause childhood apraxia of speech. Loss of Foxp2 in mice is known to affect striatal development and impair motor skills. However, it is unknown if striatal excitatory/inhibitory balance is affected during development and if...
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| Publicado no: | Brain Struct Funct |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6267273/ https://ncbi.nlm.nih.gov/pubmed/30187194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-018-1746-6 |
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