Pharmacokinetics of Sublingually Delivered Fentanyl in Head and Neck Cancer Patients Treated with Curatively Aimed Chemo or Bioradiotherapy

Over 90% of patients treated for head and neck cancer with curatively aimed chemo or bioradiotherapy will develop painful mucositis and xerostomia. Sublingually delivered fentanyl (SDL) is a rapid acting opioid to treat breakthrough pain. It is unclear how SDL is absorbed by the mucosa of these pati...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Kuip, Evelien J. M., Oldenmenger, Wendy H., Oomen-de Hoop, Esther, Verduijn, Gerda M., Thijs-Visser, Martine F., de Bruijn, Peter, van Meerten, Esther, Koolen, Stijn L. W., Mathijssen, Ron H. J., van der Rijt, Carin C. D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266947/
https://ncbi.nlm.nih.gov/pubmed/30445772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10110445
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