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Silvestrol Inhibits Chikungunya Virus Replication

Silvestrol, a natural compound that is isolated from plants of the genus Aglaia, is a specific inhibitor of the RNA helicase eIF4A, which unwinds RNA secondary structures in 5′-untranslated regions (UTRs) of mRNAs and allows translation. Silvestrol has a broad antiviral activity against multiple RNA...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Henss, Lisa, Scholz, Tatjana, Grünweller, Arnold, Schnierle, Barbara S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266838/
https://ncbi.nlm.nih.gov/pubmed/30380742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10110592
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