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Silvestrol Inhibits Chikungunya Virus Replication
Silvestrol, a natural compound that is isolated from plants of the genus Aglaia, is a specific inhibitor of the RNA helicase eIF4A, which unwinds RNA secondary structures in 5′-untranslated regions (UTRs) of mRNAs and allows translation. Silvestrol has a broad antiviral activity against multiple RNA...
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| Published in: | Viruses |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6266838/ https://ncbi.nlm.nih.gov/pubmed/30380742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10110592 |
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