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Cathepsin B-mediated CD18 shedding regulates leukocyte recruitment from angiogenic vessels

Cathepsin B (CtsB) contributes to atherosclerosis and cancer progression by processing the extracellular matrix and promoting angiogenesis. Although CtsB was reported to promote and reduce angiogenesis, there is no mechanistic explanation that reconciles this apparent discrepancy. CtsB cleaves CD18...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Nakao, Shintaro, Zandi, Souska, Sun, Dawei, Hafezi-Moghadam, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266635/
https://ncbi.nlm.nih.gov/pubmed/28904019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601229R
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