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Cathepsin B-mediated CD18 shedding regulates leukocyte recruitment from angiogenic vessels

Cathepsin B (CtsB) contributes to atherosclerosis and cancer progression by processing the extracellular matrix and promoting angiogenesis. Although CtsB was reported to promote and reduce angiogenesis, there is no mechanistic explanation that reconciles this apparent discrepancy. CtsB cleaves CD18...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Nakao, Shintaro, Zandi, Souska, Sun, Dawei, Hafezi-Moghadam, Ali
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266635/
https://ncbi.nlm.nih.gov/pubmed/28904019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601229R
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