Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays

Lassa virus (LASV), a mammarenavirus, infects an estimated 100,000–300,000 individuals yearly in western Africa and frequently causes lethal disease. Currently, no LASV-specific antivirals or vaccines are commercially available for prevention or treatment of Lassa fever, the disease caused by LASV....

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Publicado no:Viruses
Main Authors: Caì, Yíngyún, Iwasaki, Masaharu, Beitzel, Brett F., Yú, Shuīqìng, Postnikova, Elena N., Cubitt, Beatrice, DeWald, Lisa Evans, Radoshitzky, Sheli R., Bollinger, Laura, Jahrling, Peter B., Palacios, Gustavo F., de la Torre, Juan C., Kuhn, Jens H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266387/
https://ncbi.nlm.nih.gov/pubmed/30463334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10110655
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