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A PB1-K577E Mutation in H9N2 Influenza Virus Increases Polymerase Activity and Pathogenicity in Mice

H9N2 avian influenza viruses are present in poultry worldwide. These viruses are considered to have pandemic potential, because recent isolates can recognize human-type receptor and several sporadic human infections have been reported. In this study, we aimed to identify mutations related to mammali...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Kamiki, Haruhiko, Matsugo, Hiromichi, Kobayashi, Tomoya, Ishida, Hiroho, Takenaka-Uema, Akiko, Murakami, Shin, Horimoto, Taisuke
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266086/
https://ncbi.nlm.nih.gov/pubmed/30463209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10110653
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