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Isolation and Characterization of Poecistasin, an Anti-Thrombotic Antistasin-Type Serine Protease Inhibitor from Leech Poecilobdella manillensis

Antistasin, first identified as a potent inhibitor of the blood coagulation factor Xa, is a novel family of serine protease inhibitors. In this study, we purified a novel antistasin-type inhibitor from leech Poecilobdella manillensis called poecistasin. Amino acid sequencing of this 48-amino-acid pr...

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Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Tang, Xiaopeng, Chen, Mengrou, Duan, Zilei, Mwangi, James, Li, Pengpeng, Lai, Ren
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265900/
https://ncbi.nlm.nih.gov/pubmed/30373118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10110429
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