Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone

The primary tumor microenvironment is inherently important in prostate cancer (PCa) initiation, growth and metastasis. However, most current PCa animal models are based on the injection of cancer cells into the blood circulation and bypass the first steps of the metastatic cascade, hence failing to...

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Publicat a:Cancers (Basel)
Autors principals: McGovern, Jacqui A., Shafiee, Abbas, Wagner, Ferdinand, Lahr, Christoph A., Landgraf, Marietta, Meinert, Christoph, Williams, Elizabeth D., Russell, Pamela J., Clements, Judith A., Loessner, Daniela, Holzapfel, Boris M., Risbridger, Gail P., Hutmacher, Dietmar W.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265886/
https://ncbi.nlm.nih.gov/pubmed/30428629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10110438
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