Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3G

Although the host restriction factor APOBEC3G (A3G) has broad spectrum antiviral activity, whether A3G inhibits enterovirus 71 (EV71) has been unclear until now. In this study, we demonstrated for the first time that A3G could inhibit EV71 virus replication. Silencing A3G in H9 cells enhanced EV71 r...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Li, Zhaolong, Ning, Shanshan, Su, Xing, Liu, Xin, Wang, Hong, Liu, Yue, Zheng, Wenwen, Zheng, Baisong, Yu, Xiao-Fang, Zhang, Wenyan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
RNA and RNA-protein complexes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265463/
https://ncbi.nlm.nih.gov/pubmed/30247716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky840
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