Single-cell stabilization method identifies gonadotrope transcriptional dynamics and pituitary cell type heterogeneity

Immediate-early response genes (IEGs) are rapidly and transiently induced following an extracellular signal. Elucidating the IEG response patterns in single cells (SCs) requires assaying large numbers of timed samples at high accuracy while minimizing handling effects. To achieve this, we developed...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Ruf-Zamojski, Frederique, Ge, Yongchao, Nair, Venugopalan, Zamojski, Michel, Pincas, Hanna, Toufaily, Chirine, Tome-Garcia, Jessica, Stoeckius, Marlon, Stephenson, William, Smith, Gregory R, Bernard, Daniel J, Tsankova, Nadejda M, Hartmann, Boris M, Fribourg, Miguel, Smibert, Peter, Swerdlow, Harold, Turgeon, Judith L, Sealfon, Stuart C
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265460/
https://ncbi.nlm.nih.gov/pubmed/30357357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky991
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