SOX9 expression decreases survival of patients with intrahepatic cholangiocarcinoma by conferring chemoresistance

BACKGROUND: Sex-determining region Y-box (SRY-box) containing gene 9 (SOX9) expression confers cancer stem cell features. However, SOX9 function in intrahepatic cholangiocarcinoma (iCCA) is unknown. This study investigated the effects and underlying mechanisms of SOX9 in iCCA. METHODS: SOX9 expressi...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Yuan, Xiaodong, Li, Jun, Coulouarn, Cédric, Lin, Tao, Sulpice, Laurent, Bergeat, Damien, De La Torre, Carolina, Liebe, Roman, Gretz, Norbert, Ebert, Matthias P. A., Dooley, Steven, Weng, Hong-Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265288/
https://ncbi.nlm.nih.gov/pubmed/30420613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0338-9
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