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Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies

Circular RNAs (circRNAs) are covalently closed endogenous molecules with tissue- and disease-specific expression patterns, which have potential as diagnostic and prognostic biomarkers in cancer. The molecules are formed by a backsplicing event linking the 3′-end of an exon to the 5′-end of the same...

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Publicat a:Lab Invest
Autors principals: Dahl, Mette, Daugaard, Iben, Andersen, Maria Schertz, Hansen, Thomas Birkballe, Grønbæk, Kirsten, Kjems, Jørgen, Kristensen, Lasse Sommer
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group US 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265260/
https://ncbi.nlm.nih.gov/pubmed/30087459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0108-6
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