Identification of Galectin-3 as an Auto-Antigen in IgG4-Related Disease

BACKGROUND: The antigenic trigger that drives the expansion of circulating plasmablasts and CD4(+) cytotoxic T cells (CD4(+) CTLs) in patients with IgG4-Related Disease (IgG4-RD) is presently unknown. OBJECTIVE: We sought to sequence Ig genes from single cell clones of dominantly-expanded plasmablas...

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Veröffentlicht in:J Allergy Clin Immunol
Hauptverfasser: Perugino, Cory A., AlSalem, Sultan B., Mattoo, Hamid, Della-Torre, Emanuel, Mahajan, Vinay, Ganesh, Gayathri, Allard-Chamard, Hugues, Wallace, Zachary, Montesi, Sydney B., Kreuzer, Johannes, Haas, Wilhelm, Stone, John H., Pillai, Shiv
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265117/
https://ncbi.nlm.nih.gov/pubmed/29852256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.05.011
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