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Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of ADAMTS1 Inhibitors

A disintegrin and metalloprotease with thrombospondin type I motifs-1 (ADAMTS1) plays a crucial role in inflammatory joint diseases and its inhibitors are potential candidates for anti-arthritis drugs. For the purposes of drug discovery, we reported the development and validation of fluorescence res...

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Bibliographic Details
Published in:Molecules
Main Authors: Peng, Jianhao, Gong, Lili, Si, Kun, Bai, Xiaoyu, Du, Guanhua
Format: Artigo
Language:Inglês
Published: MDPI 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264766/
https://ncbi.nlm.nih.gov/pubmed/22186957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules161210709
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